The Hellfire Rebirth event is one of the toughest challenges in Diablo 4 Season 10, featuring deadly bosses with unique abilities. Each class requires specific tactics to succeed, and adapting strategies to class strengths is essential.

Barbarians benefit from high durability and melee-focused combat. Against bosses with heavy fire attacks, rotating defensive skills such as Iron Skin helps mitigate damage. Leap or Charge abilities also allow quick repositioning, essential for avoiding area-of-effect flame strikes.

Rogues thrive on mobility and burst damage. Using Dash to maintain spacing prevents being caught in fire zones, while Poison Imbuement stacks quickly wear down boss health. Precision aiming during critical moments ensures bosses fall before overwhelming the battlefield with minions.

Sorcerers excel in ranged combat but must carefully manage positioning. Teleport allows instant relocation when bosses unleash wide flame arcs. Building around Fire Resistance while stacking Lightning or Frost damage gives Sorcerers the edge, especially when bosses are immune to burn effects.

Druids offer versatility. Shapeshifting forms allow tanking or ranged engagements depending on the encounter. Cyclone Armor proves particularly useful against fire-heavy bosses, while summoning companions provides additional pressure during drawn-out fights.

Necromancers bring unique advantages with their army of minions. Properly positioning skeletons to draw aggro while players stay at range ensures minimal direct damage. Curses further weaken bosses, and Bone Spear provides consistent ranged damage output.

Boss tactics also involve resource management. Saving ultimate skills for the second half of fights, when bosses become more aggressive, is often the deciding factor between success and failure. Proper timing of potions, cooldowns, and defensive buffs ensures consistent survivability.

Co-op strategies differ slightly. Groups should assign roles, ensuring that one player focuses on damage mitigation while others handle ranged DPS. Communication regarding boss mechanics, such as when flame waves are incoming, allows all members to avoid unnecessary damage.

Mastering these tactics across classes ensures victory in the Hellfire Rebirth event. Understanding class strengths, boss mechanics, and team coordination results in efficient clears and consistent access to the event's powerful rewards.